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Registration Number

0224U031753, 0122U001561 , R & D reports

Title

Development of a multisensory system based on a highly efficient recombination transducer for liquid analytes and metabolite screening

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Head

Lytvynenko Serhii V., Кандидат фізико-математичних наук

Registration Date

11-06-2024

Organization

Taras Shevchenko National University of Kyiv

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A theoretical model that describes the operation of the recombination sensor under conditions of variable signal illumination and constant illumination is proposed. A portable lighting unit was created for the testing of biological substances using complex algorithms for surveying the working surface. The physical and technological properties of the interface and the sensor system were optimized to solve the actual problems of testing analytes of biological origin. Carbon nanoparticles with a surface modified by functional groups were obtained, and methods of modifying the silicon surface for sensor systems electronic language. Algorithms for using constant illumination were developed to influence the recombination properties of the interface and obtain additional data about the analyte. For the first time, using a self-consistent approach (Poisson's equation in the space charge region and Shockley statistics), the dependence of the photocurrent on the recombination properties of the surface will be obtained The activity of LDH Lactate dehydrogenase for signal illumination and constant illumination was determined. Detection is possible due to the fact that LDH catalyzes the reaction of the transfer of the hydride ion from NADH nicotinamide adenine dinucleotide to the C2 atom of pyruvate with the formation of lactate and NAD+. 

Product Description

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Zaderko Oleksandr М.
Kozynets Oleksii V.
Sus Bohdan B.
Tsymbaliuk Olha V.

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2024-06-11