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Registration Number

0224U031468, 0121U110081 , R & D reports

Title

Personalization of treatment of patients with endometrial cancer by detection of signal lymph nodes and the use of new informative molecular biological markers of aggressiveness of the disease.

Head

Svintsitskyi Valentyn S., Доктор медичних наук

Registration Date

30-04-2024

Organization

National Cancer Institute

Description

The object of the study is cancer of the uterine body. The purpose of the work: to increase the effectiveness of treatment of patients with endometrial cancer of intermediate and high-intermediate risk groups by detecting signal lymph nodes and taking into account molecular biological factors associated with a high risk of aggressive course. Scientific hypothesis: recurrence-free survival in patients who underwent biopsy of mapped lymph nodes with indocyanine green is not less compared to patients who underwent systemic lymph node dissection, and the quality of life is better. Research methods: general clinical, pathomorphological, endoscopic, radiation, polymerase chain reaction method. Effectiveness: medical - reducing the number of systemic lymphodesections, improving long-term results in patients with RE by personalizing surgical treatment and determining molecular biological factors; social - reducing the number of postoperative complications, improving the quality of life of patients; economic: reducing the length of stay of patients in the hospital, reducing the frequency of postoperative complications, reducing the disability of patients and, accordingly, social payments from the state budget of Ukraine.

Product Description

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Yehorov Mykhailo O.
Ivankova Valentyna S.
Baranovska Lidiia M.
Dermenzhy Tetiana V.
Lyhyrda Nataliia F.
Nespriadko Serhii V.
Renkas Olena Р.
Khoptiana Olha І.
Tsip Nataliia P.