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Registration Number

0209U010600, 0105U008713 , R & D reports

Title

To work out the methods of biological welding for tissues, regional and endolymphatic therapy in complex treatment of malignant growth of basic localization (randomized trial)

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Head

Bondar Grigorij Vasiljovich, Dumansky Yurij Vasiljovich,

Registration Date

16-12-2009

Organization

Donetsk National Medical University after named Gorky

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OBJECT: patients with breast cancer and large bowel cancer. OBJECTIVE: to improve the treatment results of breast cancer and of large bowel cancer via the usage of advanced complex treatment regimen and surgical approach at the expense of special biological welding suite for medical prescription. RESULTS: the regional neoadjuvant polychemotherapy in patients with locally advanced and primary inoperable breast cancer has been improved significantly the long-term medical results in comparison with patients received neoadjuvant system polychemotherapy. The results of five-years survivability have been framed 52,3+3,4 % and 35,2+6,2 %, respectively. The effects of randomized trial have been demonstrated an absence of benefits between regional polychemotherapy and system polychemotherapy in adjuvant regimens. The developed variants of neoadjuvant chemoraytherapy for large bowel cancer haven't been worsen the firsthand treatment results: postoperative complications - 18,5 %, lethality - 3,2 %. The long-term effects would be investigate in five-years hour of observation. Due to implementation of biological welding for tissues in oncoproctology it has been obtained the reduction of intraoperative blood loss, surgical time, numbers of traditional sutures. NOVELTY: the new devices of complex treatment of breast cancer and of large bowel cancer have been worked out. EFFICIENCY: the increment of five-years survivability for patients with locally advanced and primary inoperable breast cancer on 17 %. FIELD OF APPLICATION: oncological foundations.

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Башеєв Володимир Харитонович
Бондар Григорій Васильович
Борота Олександр Васильович
Думанський Юрій Васильович
Кудряшов Олексій Георгійович
Попович Олександр Юлієвич
Сєдаков Ігор Євгенович
Семікоз Наталія Григоровна
Центіло Віталій Миколайович
Яковець Юрій Іванович

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2020-04-02