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Registration Number

0306U008642, 0103U002383 , R & D reports

Title

Substantiation and working out of organoprotective technologies of anesthesia and intensive therapy inclding the usage of hyperbaric oxygenation (HBO), plasma replacements with a function of oxygen carrier, ozone in the patient of defferent age groups in critical states.

Head

Snisar Volodymyr Ivanovych,

Registration Date

13-12-2006

Organization

Dniepropetrovsk State Medical Academy

Description

265 adults and children in a critical condition (burn illness, ischemic stroke, saccharine diabetes, preeklampsiya, surgical pathology, thoracic trauma) was inspected. Central and peripheral hemodynamic, external breathing, processes of oxidizing-restorations, psychoneurological status, the indexes of pain were studied. Research results: We are develop organoprotective technologies of intensive therapy with the use of perftoran, neuroprotectors, ozone, salts and special balanced solutions, that allowed to improve the results of treatment, shorten time of stay of patient in permanent establishment on 2 days with the decline of expenses on treatment on the average on 10%. The offered charts of anaesthetizing improved a flow intra- and postoperative periods with the decline of amount of complications on 12%. Novelty: It is set that the dynamics of indexes of psychoemotional sphere for patients with heavy burns allows to forecast the flow of illness. Degree of introduction: in Ukraine: Dnipropetrovsk andvov regions. Practical recommendations: For providing of intraoperative organoprotection at patients of onkosurgical type with heavy respirator dysfunction intravenous introduction of plasma substitute solutions is expedient with the function of carry of oxygen - perftoran. For providing of adequacy of perioperative period conducting of the permanent monitoring of pain syndrome and sedation is needed in the different groups of ages. At patients with burn posthypoxic hypoxia and violations of cerebral circulation of blood by ischemic type in a sharp period as neuro- and organoprotectors introduction of thiocetam is shown. Application domain: anesthesiology, intensive therapy, surgery, neurology. Conclusions: The use of neuroprotektors and organoprotectors (perftoran, thiocetam, reamberin, ozone) allows to decrease the amount of complications, staying patients in hospital, promote an economic effect. Application of the offered methods of anaesthetizing is promoted by quality of intra- and postoperative periods

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