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Information × Registration Number 0119U102721, ( 0220U103191  0221U105179  ) R & D request Title Computer simulation of many-particle systems with Coulomb interaction: from plasma to biological macromolecules Head Chernyak Oleksandr M., Registration Date 25-07-2019 Organization Bogolybov Institute for Theoretical Physics of NASU popup.description1 The purpose of this work is to study particle transport caused by a random electric field and to study the influence of an external electric field on the mechanics of a DNA macromolecule. A correct approach to anomalous transport that is caused by strong turbulent fields is needed to estimate a plasma confinement time in the fusion devices. The models that based on microscopic approach are used to study basic mechanisms of such transport. For low-intensity fields in these approaches, the assumption of Gaussian process is applied, which is not valid for intensive low-frequency fields. The particle trapping is the reason of anomalous transport in these fields that demonstrated in previous studies. This effect is most pronounced in a two-dimensional transport by a random electric field across magnetic one, for which we formulated analytical approximation. We aim for generalization of our approximation to account the particle motion along magnetic field and for analysis of effects of this motion on different groups of trapped particles. DNA macromolecule always exposed to external factors during a life cycle of a cell: mechanical forces, local electric fields, the formation of stable complexes with medium molecules. In media of cell, a form of a double helix is stabilized - a secondary structure of DNA by water molecules and the counterions. Shape, presence of mechanical tension in a structure and stability of a double helix depend on a configuration of a medium. Since the DNA macromolecule is the main carrier of genetic information in the cell and changes in its stability can affect all vital physiological processes, the interaction of the DNA macromolecule with the environmental molecules requires a fundamental study by modern methods of computer modeling. In particular, it is important to investigate the process of the action of an external electric field on the mechanics of a DNA macromolecule in an ion-hydrated solution by the method of molecular dynamics. popup.nrat_date 2024-12-10 Close