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Information × Registration Number 0120U102950, ( 0224U032409  ) R & D request Title Molecular biotechnology for suppression of tumors growth and chemo resistance through inhibition of endoplasmic reticulum stress Head Minchenko Oleksandr H., Доктор біологічних наук Registration Date 18-06-2020 Organization Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine popup.description1 The aim of this work is to use molecular and biotechnological approaches to inhibit glioma cell proliferation and reduce chemoresistance by inhibiting ERN1-mediated endoplasmic reticulum stress signaling as one of the major factors of tumor growth, in particular in the use of genetic constructs based on the ERN1 cytoplasmic enzymatic domains and new compounds to reduce chemoresistance. popup.nrat_date 2024-12-10 Close