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Information × Registration Number 0120U104548, ( 0220U104320  0221U106622  ) R & D request Title Molecular components of invadopodia as prognostic factors for human malignant breast cancer Head Rynditch Alla V., Доктор біологічних наук Registration Date 26-10-2020 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description1 The aim of the project is to characterize the components of invadopodia as novel biomarkers for the evaluation of metastatic potential of breast cancer tumours. The project is based on the identification of the role of TKS4, its isoform TKS4b and verprolins WIP and CR16 in the formation of protein complexes during endocytosis and vesicular transport that control the formation of invadopodia, as well as the analysis of TKS4, TKS4b, WIP, and CR16 expression in human breast cancer tumours that differ in the level of aggressiveness and metastasis. popup.nrat_date 2024-12-10 Close