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Information × Registration Number 0120U105116, ( 0220U104473  ) R & D request Title Determine the number of NETs and extracellular DNA in the circulating blood in rats at ARDS modelling, study of the inhibitory activity of promising ligands against PKCB, evaluation of the effect of PKCB-active compounds on the induction of NETs in culture, estimation of dose-dependent effect. Head Pashevin Denis О., к.мед.н. Registration Date 25-11-2020 Organization Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine popup.description1 Detection of small molecule inhibitors of protein kinase C beta (PKCB) as a key enzyme for neutrophilic granulocytes activating with the formation of neutrophil extracellular traps (NETs), for physiological testing, optimization of selected compounds and experimental therapy of acute respiratory distress syndrome (ARDS). popup.nrat_date 2024-12-10 Close