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Information × Registration Number 0121U111534, ( 0223U003243  ) R & D request Title Real-time sensor based on the latest nanoparticles for anthrax and tuberculosis Head Hunko Volodymyr M., д.х.н. Registration Date 12-06-2021 Organization Chuiko Institute of Surface Chemistry of NAS of Ukraine popup.description1 The project aims to develop an inexpensive, easy-to-use biosensor prototype that allows the identification of tuberculosis and anthrax pathogens in bioassays of living organisms in minutes to facilitate their treatment in a short time. The sensor will be based on the detection and capture of magnetically controlled magnetic nanoparticles, the surface of which is covered with a layer of gold / silver, pathogen-specific DNA sequences that have been isolated from bacteria due to direct microwave ablation. After capture of the target DNA, magnetically sensitive nanoparticles are selected from the sample using a magnet. This approach allows you to concentrate and wash the target DNA for identification. The main goal of our working group is the synthesis of magneto-controlled micro / nanoparticles of the “core-shell” type using magnetite, cobalt ferrite or nickel as a magnetically sensitive core, the surface of which is covered with a layer of gold / silver, and the study of their interaction with specific DNA probes to optimize the subsequent capture of target DNA. popup.nrat_date 2024-12-09 Close