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Information × Registration Number 0122U000664, ( 0224U001553  ) R & D request Title Molecular and cellular bases of development of socially significant human diseases and creation on this basis of modern nanobiotechnologies for prevention, diagnosis and treatment Head Telehieiev Henadii D., Доктор біологічних наук Registration Date 28-01-2022 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description1 The aim of the work is to study the molecular and cellular bases of the development of socially significant human diseases and to create on this basis modern nanobiotechnologies for prevention, diagnosis and treatment. Development of approaches to the creation of electrochemical biosensors for direct detection of substrates and inhibitory analysis of toxic substances in environmental monitoring. Development of conditions for long-term cultivation of Rauwolfia snake tissue cultures, development of methods for isolation of target and major alkaloids. Analysis of the association of polymorphic gene variants (ZNF469, ACE1) in a group of patients with cases of keratoconus of varying severity. Analysis of the expression of key enzymes of redox metabolism (REDOX) in tumor cells, which is sensitive to chemoradiotherapy. popup.nrat_date 2024-12-09 Close