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Information × Registration Number 0122U002100, ( 0222U005134  0223U005003  ) R & D request Title New antimicrobial heterocyclic compounds against multidrug-resistant bacterial strains: synthesis, in silico, in vitro studies Head Hodyna Diana M., к.б.н. Registration Date 18-03-2022 Organization V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine popup.description1 In silico design and in vitro evaluation of new antimicrobial agents with high bioactivity potential and a specific mechanism of molecular action. Development of new QSAR models of activity as a quality tool for the design and identification of new antimicrobial bioregulators among a number of azole, pyrrole and quinolone derivatives. Identification of newly synthesized compounds as effective antimicrobial agents especially against multidrug-resistant intra-hospital bacterial strains with a specific molecular mechanism of action based on QSAR prediction and experimental study. popup.nrat_date 2024-12-09 Close