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Information × Registration Number 0123U102781, ( 0223U005507  0224U032702  0225U004515  ) R & D request Title Cellular and molecular mechanisms of vitamin D3 hepatoprotective action in non-alcoholic fatty liver disease associated with experimental type 2 diabetes mellitus Head Shymanskyi Ihor O., Кандидат біологічних наук Registration Date 06-06-2023 Organization Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine popup.description1 To more fully elucidate the mechanisms of the hepatoprotective action of vitamin D3 in NAFLD associated with experimental type 2 diabetes mellitus, based on the study of the macro- and microstructure of the liver, the intensity of free radical processes, ER stress, autophagy, inflammation, apoptosis and cell proliferation in liver tissue depending on the state of the vitamin D auto-/paracrine system, as well as its modulating effects on RANKL/RANK/OPG and NF-κBmediated cellular signaling. popup.nrat_date 2024-12-09 Close