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Information × Registration Number 0124U000206, ( 0225U000188  0226U000274  ) R & D request Title 2-(2Н-Azirin-2-іl)-pyrimidin-4(3Н)-оnes. Synthesis and properties. Head Yavolovskyi Arkadii O., Доктор хімічних наук Registration Date 11-01-2024 Organization Physico-Chemical Institute O. Bogatsky National Academy of Sciences of Ukraine popup.description1 The aim of planned research is development of methods for synthesis 2-(2H-azirin-2-yl)-pyrimidines and study their main properties. Compounds 2H-azirin class belong to biologically active substances of natural origin with high antibacterial, fungicidal, and cytotoxic activity. The main idea of research is to obtain 2 (2H-azirin-2-yl)-pyrimidines by cyclization of 2-(2-hydroxyimino-2-arylethyl)pyrimidin-4(3H)-ones. Available derivatives of 2-(2-oxo-2-arylethylidene)-2,3-dihydro-1H-pyrimidin-4-ones are expected to be used as starting reagents. popup.nrat_date 2024-12-09 Close