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Registration Number

0124U004173, ( 0224U032893  0225U004214  ) R & D request

Title

Highly homologous paralogs of translation elongation factor 1A. Structural studies to understand functional differences.

Head

Negrutskii Borys S., д.б.н.

Registration Date

30-09-2024

Organization

Institute of Molecular Biology and Genetics of NAS of Ukraine

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The aim of the project is to define the structural organization of eEF1A1 and eEF1A2 in solution by creating their high-quality, experimentally validated structural models. We aim to precisely identify the structurally dynamic regions in both proteins, find out their differences, and show possible functional consequences of these differences for protein synthesis.

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2024-12-09