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Registration Number

0124U004341, ( 0224U032864  0225U004216  ) R & D request

Title

Study of the mechanisms of action of new genes involved in the regulation of riboflavin synthesis in the flavinogenic yeast Candida famata

Head

Fedorovych Dariya V., д.б.н.

Registration Date

09-10-2024

Organization

Institute of Cell Biology of the National Academy of Sciences of Ukraine

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To investigate the interaction of the previously identified transcription factor Sef1 with the promoters of the structural genes of riboflavin synthesis. To identify new genes involved in the regulation of riboflavin biosynthesis in the flavinogenic yeast Candida famata and to study their mechanisms of action by cloning and modifying them. To study the phenotypes of the obtained strains, namely, the accumulation of riboflavin, the activity of enzymes and the expression of the corresponding structural genes, as well as the content of iron in the cells.

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2024-12-09