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Information × Registration Number 0125U001845, R & D request Title Toxicological and hygienic assessment of dermal penetration of pesticides from the pyrethroid, tiazole, and organophosphorus classes using computational models and experimental methods Head Ishcheikin Kostiantyn Ye., д.мед.н. Registration Date 24-03-2025 Organization Kundiev Institute of Occupational Health of the National Academy of Medical Sciences of Ukraine popup.description1 Study of the features of dermal penetration of pesticides from the pyrethroid, triazole, and organophosphorus classes in experiments depending on their chemical composition; assessment of the potential adverse effects of dermal penetration of pyrethroid, triazole, and organophosphorus pesticides on human health; understanding the processes and mechanisms underlying the penetration of these substances through the skin for the further development of an algorithm for computational-mathematical models to predict dermal penetration of pesticides based on their chemical properties and the physicochemical parameters of the skin (molecular weight, water solubility, melting point, vapor pressure, octanol/water partition coefficient) using reliable Information sources (EFSA – European Food Safety Authority) and the pesticide properties database (PPDB). popup.nrat_date 2025-03-24 Close