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Information × Registration Number 0126U000873, R & D request Title Medico-Social Substantiation of Optimization of the Model of Medical Care for Patients with Post-Traumatic Stress Disorder Taking into Account Molecular Genetic Risk Factors Head Vladyslav A. Smiianov, д.мед.н. Registration Date 27-01-2026 Organization Sumy State University popup.description1 Determination of the role of single nucleotide polymorphisms in genes of the hypothalamic–pituitary–adrenal (HPA) axis (CRHR1 (rs1724402), FKBP5 (rs1360780), etc.) in the pathogenetic mechanisms underlying the development of post-traumatic stress disorder; identification of associations between genotypes of the studied polymorphisms (SNPs) and clinical characteristics of the course of PTSD, as well as the detection of correlations between the most prevalent risk factors and these associations. The results will provide a basis for determining the prognostic value of the identified SNPs, stratifying high-risk groups, and for the medico-social substantiation of optimization of the model of medical care (improvement of early diagnosis and development of personalized strategies for prevention and treatment) for patients with PTSD popup.nrat_date 2026-01-27 Close