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Information × Registration Number 0200U001299, 0197U003399 , R & D reports Title Development of the Principles and Methods of Antiradiation Means assessment. popup.stage_title Head Rudnev M.I., Registration Date 18-05-2000 Organization Research Centre for Radiation Medicine popup.description2 Goal: to study changes of the functional state of the cen-tral nervous system, endocrine, metabolic, cytogene-tic, hematologic indices under exposure to ionizing radi-ation of wide dose range for the development of the prin-ciples and techniques of correction means effective-ness assessment. Methods: neurophysiological, endocri-no-lo-gi-cal, biochemical, cytogenetic, radiobiological. The technique of central nervous system function studies in animals was improved. Stimulating effect of low doses (0.1 and 0.5 Gy) and inhibitory of moderate doses (1 and 5 Gy) was found at removed terms. The change in thy-roid gland sensitivety to specific drugs was found at exposure to different doses. Dose dependent increase of the number of the cells with nuclear damages was shown in 5, 20 and 30 days after exposure (0,1-5 Gy). Microcalorimetric technique of brain tissues studies is a sensitive one for ionizing radiation (0.1 Gy) effects assessment 30 days later. The obtained data will be used as criteria for antiradia tion means assessment. Product Description popup.authors popup.nrat_date 2020-04-03 Close