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Information × Registration Number 0200U001435, 0197U004292 , R & D reports Title Synthesis and study of the interaction mechanism of cyanine fluorescent probes with nucleic acids popup.stage_title Head Yarmolyuk S. M., Registration Date 17-02-2000 Organization Institute of molecular biology & genetics popup.description2 Monomethyne cyanines are the most sensitive fluorescent dyes for nucleic acids detection among currently availiable. Basing on obtained data we proposed the model of half-intercalative interaction of cyanines with dsDNA. We also proposed several new dyes as fluorescent probes for nucleic acids detection. Besides that the new original method of covalent labeling of aminoalcyloligonucleotides with the pirilium cyanine dyes was developed. Branch : biology Product Description popup.authors popup.nrat_date 2020-04-03 Close