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Information × Registration Number 0200U001851, 0197U006497 , R & D reports Title Analysis of the genomic disturbances in malignant lymphoma cells and upon apoptosis induction popup.stage_title Head Butenko Z. A., Registration Date 04-04-2000 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Apoptosis in B- and T-cell leukemia and lymphoma lines has been analysed morphologically as well as by the results of the flow cytometry and DNA fragmentation. The susceptibility of B- and T-cell lines to the induction of the apoptosis by etoposide turned out to be quite different. c-myc rearrangements due to the effects of the subtoxic doses of etoposide have been revealed. At the same time prolonged incubation of the cells with retinoids have been shown to result in specific rearrangements of bcl-2 and c-myc Product Description popup.authors popup.nrat_date 2020-04-03 Close