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Information × Registration Number 0200U003563, 0198U005758 , R & D reports Title Adaptive changes of connective tissue support proteins metabolism and structure under the influens of extremal factors. popup.stage_title Head Pers'kyj Ye.E., Registration Date 07-06-2000 Organization Kharkov National University named after V.N. Karazin popup.description2 Object of study - collagen and elastin structures of aorta of Wistar line white rats. Aim of study -to investigate structural and metabolic mechanisms of aorta collagen and elastine structures adaptation to the influence of the mechanical load in vitro. Methods of study -izotope exchange imino and amino acid analysis and others. It was shown,That the dependences of collagen and elastin concentrations and synthesis intensitie of these proteins from the mechanical load are the graphs with maximums.At the same time the influence of the mechanical load leads to the level of proline hydrohulation in collagen and collagen cross-linking.Dynamic of tyrozin concentration dependence from the mechanical load is the graph with minimum . At the first time it was shown that complexes Ca/calmodulin takes place in collagen sinthesis. Product Description popup.authors popup.nrat_date 2020-04-03 Close