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Information × Registration Number 0200U004788, 0100U006019 , R & D reports Title Study of effects of chronic radiation influence on the state of different systems and organs of the experimental animals. Assessment of remote consequence of influence of the Exclusion Zone factor complex on the living organisms. Assessment of state of ethmofauna and pathogenic diseases of plants of the Exclusion Zone phytocenosis and at the ecotopes of abandoned settlements. Phytosanitary monitoring of forest plantations. popup.stage_title Head Karpenko N.O., Registration Date 27-11-2000 Organization State Specialized Scientific-Industrial Enterprise "Chornobyl radioecological Centre" popup.description2 It have been modelled the situation of chronic alimentary influx of radionuclides to male Wistar rats and investigated dynamic of radiobiological effects in different systems and organs after 1.5, 4 and 12 months. It was established reducing of stress-limited GABA system activity in some rat brain structures which progressed according to irradiation period. It was described direction and degree of phase change of morfofunctional state of pituitary-adrenal system. It was noted negative influence of internal and external irradiation on male sexual behaviour, spermatogenesis and fertility. It was disclosured changes in cytogenetic indexes, gametes DNA and mutagenic effect on posterity. Adult offsprings were more sensitive to irradiation than their parents. One year irradiation induces the thyroxin deficit and development of oxidative stress in animals. Early application of adaptogen (spirulina biopolymer) prevents disturbance caused by irradiation. It was marked early stage of stress of compensation mech anisms. Product Description popup.authors popup.nrat_date 2020-04-03 Close