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Information × Registration Number 0200U007011, 0199U001448 , R & D reports Title Chronopharmacology of melatonin: the effect on the neurohormonal regulation of endocrine functions system popup.stage_title Head Bondarenko Lyudmyla Oleksandrivna, Registration Date 29-12-2000 Organization Ukrainian Research Institute of Endocrine Diseases Pharmacotherapy popup.description2 Object: Wistar rats. Aim: Studying the effect of melatonin in different doses on functional activity of peripheral endocrine glands and their regulating centers depending day time and season and on this base reasoning the importance of using this preparate in endocrine practice. Methods: biochemical, morphological, radioimmunological, biophysical. It was shown, that low doses of melatonin normalizes the hormonal function (that is decreased because of age) because of an increase of anti-radical activity and the stimulation of organism antioxidant system. Field of using: physiology, endocrinology, gerontology Product Description popup.authors popup.nrat_date 2020-04-03 Close