Search academic texts

Information × Registration Number 0201U001848, 0198U001756 , R & D reports Title To develop medico-engineering technology of mechanochemical modification of biologically active substances for use in combined treatment of cancer patients. popup.stage_title Head Orel V. E., Registration Date 22-02-2001 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 The object of study: Doxorubicin (DR) and syngenic tumor cells (STC) after mechanochemical modification (MM), cells Hep-2, rats with Guerin's carcinoma, patients with colonic, stomach, breast cancers and malignant lymphomas. The aim is to develop medico-engineering technology of bilogically active substances for use in combined treatment of cancer patients. Methods of examination - clinical, physico-chemical, statistical. Instruments: micromill MMVE-0,005, diphractometr DRON-2.0, spectrometr SPECORD M40, IR-spectrometr UR-20, spectrofluorimetr SDL-2. MM DR and STC technology has been developed. The improvement of the immediate results of treatment and decrease of side effects (leukopenia, erythropenia, ECG changes). Field of application - oncologic hospitals. Product Description popup.authors popup.nrat_date 2020-04-02 Close