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Information × Registration Number 0201U003013, 0198U007887 , R & D reports Title The eleaboration of optimal technology technology of production of nalo[ove and naltrexone, their medicines forms with action and creation on this basis the new method of antirelapse treament of opiate addiction/ popup.stage_title Head Pervomajskyj E.B., Registration Date 25-01-2001 Organization Ukrainian SRI of Clinical and Experimental Neurology and Psychiatry popup.description2 It is studied on experimental animals(200 white rats of Wistar lines) the duration of specific action of 7 cjmplex ethers of naloxone and organic acides with different molecular weight, which was used as injectible medicines forms creams on the basis sesame olium and ethiloeat. The ait of investigation is creation of method of antirelapse treament of opiate addiction Methods of investigation are organis synthesis high perfomance liquid chromatography, chronic and acute behavioral experiments. The results--in established that bigest duration of action supplies ether of nalovone and threedecanoic acid(17 daes). This result is new. The application on patente is preparing now/ The implementation-the technology of production of medicines form of long acting naloxone was implemented on the Kharkiv"s State Phaemacceutial Company"Zdorovye varodu". Fiedsofusing-hlanmacjlogy and nargology Product Description popup.authors popup.nrat_date 2020-04-02 Close