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Information × Registration Number 0201U003558, 0197U001157 , R & D reports Title Study on the effect of apoA1 gene and insulin gene implantation on protein biosynthesis and the state of hepatocyte plasmatic membranes in animals of different age popup.stage_title Head V.V.Bezrukov, Registration Date 22-03-2001 Organization Institute of Gerontology popup.description2 The results obtained show the essential changes in functional state of hepatocyte's plasmatic membrane due to the implantation of human apoAI gene to rat liver. The changes in phospholipids composition, hyperpolarization, increase in activity of membrane bound enzymes, cytochrome P-450 and biosynthesis of liver total proteins have been found. The essential changes characterize cell's effect was more marked in adult rats, and membrane's effects in old rats. norm and during hypercholesterolemia development have been elucidated. Product Description popup.authors popup.nrat_date 2020-04-02 Close