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Information × Registration Number 0202U000405, 0199U003951 , R & D reports Title Physico-chemical, moleculobiological and the mathematical analysis of the most general characters of P(hysiological)A(ctive) S(ubstances) interaction with biomacromolecules popup.stage_title Head Lujk O.I., Registration Date 05-02-2002 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 The study of features of influence of physiologicall active substance carbachol - agonist of cellular outer membrane acethylcholine receptors of M-type - on conformation dynamics of human serum albumin was carried out. It was shown, that low-frequency acoustic in water solutions of albumin is caused by cooperative conformational transitions in protein chain. It was established, that carbachol blocks conformationally mobile segments protein chain and interferes with their participation in cooperative transitions in albumin molecule. Product Description popup.authors popup.nrat_date 2020-04-02 Close