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Information × Registration Number 0202U006716, 0100U000009 , R & D reports Title Working out effective methods of endothelium and organ-targets disturbances pharmacological correction in hypertension and heart failure popup.stage_title Head Berezov V.M., Registration Date 11-12-2002 Organization Donetsk state medical University named after M. Gorky popup.description2 On the base of investigation of 378 hypertensive patients, 84 patients with attendant osteoarthritis and 124 patients with heart failure it has been determined a leading role of endothelium dysfunction in the beginnings of the phenomenon of the silent myocardial ischemia in hypertension and nitric oxid synthesis stimulators effectiveness for their correction. There were determined prostaglandin-dependence during therapy with cyclooxyhenaze inhibitors and their prevention. There were described tree regimens of renal function and renin-related renal function in heart failure. There were specified mechanisms of enalapril, losartan and metoprolol influence on sodium and water excretion. Product Description popup.authors popup.nrat_date 2020-04-02 Close