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Information × Registration Number 0203U000239, 0100U001582 , R & D reports Title To study the causes and pathogenetic mechanism of the development of resistance to replacement therapy in patients with hemophilia, and to work out the methods of prophylaxis and treatment of hemorragic manifestations in this complication. popup.stage_title Head Evstakhevych Igor Josiphovich, Registration Date 04-01-2003 Organization LVIV RESEARCH INSTITUTE OF BLOOD PATHOLOGY AND TRANSFUSIONAL MEDICINE popup.description2 The causes and pathogenical mechanismes of resistence to replacement therapy in haemophiliacs, caused by appearance of immune inhibitors to coagulation factors, confirmity with clinical and immunological manifestations in dynamic of hemorrhagical diathesis was studed. The effectiveness of methods of neutralization of inhibitors depending on primary titre of inhibitors and type of immune responding of patients to replacement therapy was studed. Product Description popup.authors popup.nrat_date 2020-04-02 Close