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Information × Registration Number 0204U003721, 0100U002246 , R & D reports Title The influence of heavy metals lead, mercury, manganese and iron as toxic environmental factors on age adaptation changes and life expectancy (experimental and clinical hygienic investigations) popup.stage_title Head Isaac M. Trachtenberg, Registration Date 16-04-2004 Organization Institute for Occupational Health of the Academy of Medical Sciences of Ukraine popup.description2 Age related differences in animal reactions on exposure to heavy metals lead, mercury, manganese were established using various biochemical, immunological, electrocardiographical, morphological metods. Shift depth and dynamics was more distinct in old animals than in young and was influenced by particular metal. The most indices were influenced by mercury and lead derivatives, while manganese mainly influenced on cardiovascular system. These reactions are mainly predetermined by the peculiarities of adaptation mechanisms of each age group. Morphological indices, which reflect intensity of reparatory processes in liver tissue, were more reflective in young animals and this promoted normalization of ogran structure, approaching the control level at the end of experiment Product Description popup.authors popup.nrat_date 2020-04-02 Close