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Information × Registration Number 0204U006157, 0103U001593 , R & D reports Title To learn neurohumoral and haemodynamics gears of development of a syndrome of a cachexia for ill with a chronic heart failure and to elaborate the reasonable of pathogenic methods of its medicament correction. popup.stage_title Head Gorb Yuri G., Registration Date 29-07-2004 Organization Institute of therapy of Academy of medical science of Ukraine popup.description2 The study of trophological status, left ventricular systolic and diastolic function and heart rate variability in 40 patients with chronic heart failure (CHF) of I - IV functional classes has been carried out.30 healthy subjects consisted the control group. It is established that approximately in 10% of CHF patients have the manifestation of cardiac cachexia syndrome, which was assessed by medical history data (body mass decrease of more than 7,5% in comparison with the previous value during 180 days), and the results of anthropometric examination (body mass index < 18 kg/m2). In the process of CHF progression left ventricular dilatation increased, as well as the degree of its systolic and diastolic dysfunction, and indices describing trophological status of patinets. The decrease of general heart rate variability and its parasympathetic component also decreased, which directly correlated with the severity of clinical and haemodynamic disturbances. The difference of this study form the known analoguesis the complex approach to the study of mechanisms of the cachexia syndrome in patients with CHF, based on the study of trophological status, systolic and diastolic myocardial functions and vegetative status. Product Description popup.authors popup.nrat_date 2020-04-02 Close