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Information × Registration Number 0205U004772, 0100U000793 , R & D reports Title Comparative studies of substrate specific recognition and catalysis mechanisms by class 1 and 2 aminoacyl-tRNA synthetases. popup.stage_title Head Tukalo Mikhaylo, Доктор біологічних наук Registration Date 24-05-2005 Organization Institute of molecular biology & genetics popup.description2 Comparative studies of molecular substrates recognition mechanisms by class 1 (LeuRS and TyrRS) and class 2 (HisRS and ProRS) T.thermophilus aminoacyl-tRNA synthetases in solution and crystals have been carried out. It has been demonstrated at the first time, that the recognition of substrates by aminoacyl-tRNA synthetases has not only "key - lock" mechanism but the mechanism of "induced-fit" as well. A non-canonical type of tRNA recognition by tyrosyl-tRNA synthetases has been demonstrated. Product Description popup.authors popup.nrat_date 2020-04-02 Close