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Information × Registration Number 0205U006817, 0100U006465 , R & D reports Title The investigation of the epilepsy resistant forms development on the experimental status epilepticus and postkindling in different ages rats with the aim of their cessation pharmacological treatment performing out. popup.stage_title Head Shandra Alexey Antonovich, Registration Date 03-01-2006 Organization Odessa state medical university popup.description2 It was shown on the basis of the obtained results that convulsive syndrome formation at pups in early postnatal period has more expressed and stable character proved in conditions of generalized, chronic and posttraumatic seizures. Carbamazepin and valproic acid antiseizure effects were absent in these conditions that allows to speculate that antiepileptic mechanisms insufficiency - functional activity of the antiepileptic system as well as endogenous antiepileptic mechanisms activation - are responsible for the steady character of epileptogenesis and pharmacological "resistency" formation in rats in early postnatal period. Product Description popup.authors popup.nrat_date 2020-04-02 Close