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Information × Registration Number 0206U002291, 0102U003258 , R & D reports Title The development of synthesis thecnology of bimetalic (iron-zinc, iron-copper, manganese-zinc, manganese-copper etc.) complexonates of ethylenediaminedissuccinic acid for pharmacy. The investigation of biological activity of obtained complexes. popup.stage_title Head Mazurenko Yevgen Andrijovych, Registration Date 02-02-2006 Organization National Academy of Scienіses of Ukraine, Council of Productive Forces Studies of Ukraine popup.description2 The thecnology of synthesis of biological active commpexone (ethylenediaminedissuccinic acid (edds)) was developed. The one-stage template synthesis of monometalic complexonates of 3-d metals with edds in first time was developed. The method of synthesis of bimetalic coordination compounds of 3-d metals (Fe-Cu, Fe-Zn, Fe-Mn, Cu-Mn, Cu-Zn, Mn-Zn) was developed. The physico-chemical properties of all synthesized complexes was stidied. The region of existence of complexes in depence of pH of solution and concentration of metal was determined. Was shown, that this complexes has distorted octahedra structure. The coordination of central atoms with all funtional grups of edds was occured. In first time the method of synthesis of Pt(II) with edds was developed. The Pt(II)edds complex on this thechology was obtained Впервые рразработана методика синтеза и синтезован комплекс Pt(II) с ЭДДЯ. Определены его свойства и строение. Проведены опытно-лабораторные испытания синтезованных комплексонатов в сельскомхозяйстве и медицине. Показано, что комплексонаты являются мощными ростстимуляторами растений, увеличивая их урожайность на 30 -50%. Применение препаратов как кормовой добавки для животных способствует улучшению показателей крови (гемоглобин, эритроциты и др.), увеличению их веса на 10-15% и снижению себистоимости продукции на 8-10%. Биметальные комплексонаты обладают блокирующими свойствами относительно поступления радионуклидов в растения. Испытания железосодержащего комплекса для лечения анемии показало его более высокую эффективность по сравнению с современными лекарственными антианемическими препаратами. Результаты работи могут быть использованы для синтеза микудобрений, кормовых добавок и антианемических препаратов определенного состава с заданныи свойствами. Область применения полученных результатов: сільское хозяйство и медицина. The methods of synthesis of volatile mono- and bimemalic coordination compounds of titanium, zirconium and hafnium with b-iminoketones are developed. Is established, that synthesized binuclear complexes are sublimed without decomposition in a temperature range 150-250 0С. The quantum -chemical methods carry out to study of an electronic and geometrical structure enamiacetonates of titanium, zirconium and hafnium. The synthesis of oxynitide titanium and zirconium powders. The results of work can be used for synthesis flying precursors and reception on their basis dimensioned powder and films of the given structure by a СVD-method. Area of application of the received results: оpto- and microelectronics, radio engineering industry, machine - and aircraft construction. Product Description popup.authors popup.nrat_date 2020-04-02 Close
R & D report
Head: Mazurenko Yevgen Andrijovych. The development of synthesis thecnology of bimetalic (iron-zinc, iron-copper, manganese-zinc, manganese-copper etc.) complexonates of ethylenediaminedissuccinic acid for pharmacy. The investigation of biological activity of obtained complexes.. (popup.stage: ). National Academy of Scienіses of Ukraine, Council of Productive Forces Studies of Ukraine. № 0206U002291
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Updated: 2026-03-26