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Information × Registration Number 0206U004593, 0102U004547 , R & D reports Title New ensembles of hydrogenated pyrazolo-, 1,2,4-triazolo- and thiazoloazines popup.stage_title Head Lipson Victoria Victorovna, Registration Date 02-03-2006 Organization V.Danilevsky Institute of Endocrine Pathology Problems Academy of Medical Sciences of Ukraine popup.description2 Object of reserch: azaheterocyclic derivatives. The purpose of research: The development of the scientific foundations of the synthesis condensed systems' ensembles which contain hydrogenated 5-,6-and 7-member azaheterocycles with two, three or four nitrogen atoms. Methods: organic synthesis, IR, NMR H spectroscopy, mass-spectrometry, X-ray diffraction study. The directedness of -aminoazoles' interaction with, аlpha, вeta-unsaturated acids and ketones, in dependence of processes conditions has been revealed. Chemical properties of dihydro derivatives of pyrazolo- and 1,2,4-triazolo[1,5-a]pyrimidines and the routes of transformation of these compounds into new heterocyclic systems have been studiet. The different factors influence on the state of imine-enamine tautomeric equilibrium have been analyzed. 13-Carbox- and thiocarboxamides of the 9-methyl-11-thioaxa-8-oxa-10,12-diazatricyclo[7.3.1.02,7] trideca-2,4,6-trienes for the first time have been obtained. Product Description popup.authors popup.nrat_date 2020-04-02 Close