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Information × Registration Number 0206U009376, 0104U002238 , R & D reports Title Role of some neurohumoral factors in development of pulmonary hypertension in patients with dust lung pathology popup.stage_title Head Kostyuk Inna Fedorovna, Registration Date 27-02-2007 Organization Kharkov State Medical University popup.description2 Main patterns of development and course of dust lung pathology against peculiarities and working conditions, age and experience factors of workers were stated. Character of respiratory, cardiohemodynamic, neurohumoral disturbances was revealed. The essential role of endothelin-1 and nitric oxide in the development of hemodynamic disorders was stated. The necessity of use of these indexes as markers of neurohumoral disturbances was grounded. The most significant correlation was found between indexes of lung ventilation and average pressure in pulmonary artery, as well as between endothelin-1 blood concentration and average pressure in pulmonary artery. The method of medicamentous correction using ACE inhibitor Enalapril - medication that promote the regress of endothelium dysfunction was developed. Results of SRW were introduced into the practices of clinics of SRI of labour hygiene and occupational diseases in Kharkiv.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close