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Information × Registration Number 0206U009545, 0103U003288 , R & D reports Title Role of potential-operated potassium channels in GABA release in central neurons. popup.stage_title Head Veselovskiy Nikolay S., Registration Date 26-12-2006 Organization International center of molecular physiology popup.description2 The aim of our investigation was to study the role of voltage-dependent potassium channels in modulation of release of inhibitory neuromediator - GABA - in neurons of rat hippocampus Using immunocytochemical staining and whole-cell patch-clamp technique three types of voltage-dependent potassium channels (Kv) were identified in interneurons of the hippocampus. These channels are distinguished by their kinetics of activation and inactivation, voltage dependencies, pharmacological characteristics and modulation by intracellular secondary messengers. New data about mechanisms of inhibitory synaptic transmission, mediated by GABA release and about regulation of these mechanisms by Ca influx were obtained Results of this work add on investigation of main issues of neurophysiology: studying and memory phenomena. Materials were represented in 8 articles in foreign and national journals and 10 international and national conferences. Product Description popup.authors popup.nrat_date 2020-04-02 Close