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Information × Registration Number 0207U002456, 0102U005103 , R & D reports Title Development of convenient syntheses of functionalised asoles and asines derivatives - perspective compounds for discovering effective bioregulators popup.stage_title Head Drach B., Registration Date 31-01-2007 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 Methods of synthesis of vinylheterokumulenes of the general formula Cl2C=C(SO2Ar)N=C=X (X=O,S,NR) have been developed and heterocyclisations on the basis of the later have been studied. The accessible 2-acylamino-3-chloroacrylonitriles have been shown to be easily cyclizised by action of action of hydrazine hydrate to form early unknown 3(5)-amino-4-acylaminopyrasoles. A series of substituted pyrazolo[1,5-a]pyrimidines have been synthetised on the basis of arylsulfonylacetonitriles. Preparative sintheses of substituted imidazo[1,2-a]pyridines and their pyrimidines analogues have been developed on the basis of amidophenacylating reagents. The effective immunomodulators have been found among the new derivatives of azoles.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close