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Information × Registration Number 0207U002457, 0102U005104 , R & D reports Title Research of modelling transformations of natural and synthetic bioregulators. Fundamental bases of search and creation of new biologically active substances popup.stage_title Head Vovk A., Registration Date 31-01-2007 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 Spin labeled thiazolium salts have been synthesized and investigated in biomimetic systems. Antioxidative activity of new coumarine derivatives was established. New peptide derivatives containing heterocyclic residues were synthesized and specific antibodies up to conjugates of coumarine amino acid derivatives with diphtheritic toxin were received. Phenazine derivatives as potential nucleinic acid intercalators have been obtained. The method of obtaining of bioactive plant-derived substance of ?-3 polyunsaturated fatty acids has been developed. It was shown that enriching the diet with these substances results in modification of the membrane phospholipid fatty acid composition in vivo.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close