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Information × Registration Number 0207U004950, 0104U009677 , R & D reports Title Investigation of novel approaches to acyclic nucleosides - potential drugs of wide type activity popup.stage_title Head Drach B.S., Registration Date 25-10-2007 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 Promised methods for producing sulfur containing acyclic analogues of nucleosides were developed. High regioselelective introduction of hydroxyalkyl fragments into specific positions of a pyrimidine ring was elaborated. Techniques for isolation of intermediate phosphonium derivatives of acyclonucleosides as well as a procedure of their dephosphorilation were improved. Sulfur containing acyclonucleosides presented are closely related structural analogues of the antiviral agents HEPT.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close