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Information × Registration Number 0207U005282, 0102U000745 , R & D reports Title Endothelium-dependent mechanisms of changes of vascular tone in aging and radiation and its correction popup.stage_title Head Tkachenko Michael, Registration Date 23-03-2007 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 Present investigation deals with the study of endothelium-dependent and endothelium-independent contractile reactions of vascular smooth muscles, electrophysiological properties of aortal endothelium, levels of free radicals of oxygen and stable metabolites of nitrogen: eicosanoids, products of non-enzymic (dienic conjugates, malonic dialdehyde) and enzymic (thromboxane В2, leukotriene С4) oxidation of lipids, low molecular water soluble antioxidants (uric acid, urea) in the cells of cardiovascular system during aging in conditions of long-term effects of low doses of radiation, as well as with the protecting effects of L-arginine on vascular reactions and oxidative metabolism of oxygen and nitrogen. Product Description popup.authors popup.nrat_date 2020-04-02 Close