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Information × Registration Number 0207U006031, 0102U000629 , R & D reports Title Estimation of fibrinolysis mechanism as a scientific basis of thrombolytic therapy and development of some new thrombolytics popup.stage_title Head Kudinov S.O., Registration Date 12-03-2007 Organization A.V.Palladin Institute of Biochemistry of National Academy of Sciences popup.description2 The creation of new conseption of fibrinolytic potential regulation (FP regulation) at the normal state and at the thrombogenic pathology has been the main result of the Department's work. According to this conception the natural input of enhanced fibrinolysis process has to be developed thanks Pg concentration elevation in blood at the acute phase. This is the way of work of defensive mechanism to prevent trombotic complications. The possibility of reproduction this mechanism to regulate the velocity of thrombus lysis gives the broad perspective to create new thrombolitical preparations on the base of plasminogen. The base for using these preparation is the feature of FP deficiency, which is clinically determined. Product Description popup.authors popup.nrat_date 2020-04-02 Close