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Information × Registration Number 0207U006590, 0103U008431 , R & D reports Title Genetic contpol of biosynthesis of the new anticancer antibiotic landomycin E popup.stage_title Head Matselyuch Bogdan Pavlovich, Registration Date 08-06-2007 Organization Zabolotny Institute of Microbiology and Virology Ukrainian NAS popup.description2 The series of Streptomyces globisporus 1912 mutants defective in biosynthesis of landomycin E and genistein, resistant to antibiotics and activated in respect to silence genes of carotenogenesis were obtained under action of nitrosoguanidine and UV-light on the spores, mycelium and protoplasts. The recombinants with new combination of genes, including high active producers of landomycin E, were obtained after protoplasts fusion of different mutants. They produced 20-25% landomycin E more in comparison with initial strains Product Description popup.authors popup.nrat_date 2020-04-02 Close