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Information × Registration Number 0207U008392, 0105U001703 , R & D reports Title Development of new methods for diagnostic of atherosclerosis progression and prediction of its complications in patients with acute coronary syndromes on the basis of the detailed analysis of proteolitic processes in connective tissue popup.stage_title Head Dzyak Georgy Victorovich, Registration Date 13-12-2007 Organization Dniepropetrovsk State Medical Academy popup.description2 It has been presented that character of fibronectin fragmentation undergoes certainly qualitative changes durng hospital period of the acute myocardical infarction and in addition it independently determines features of the clinical disease course. The features of fibronectin fragmentation at the first day of the disease was shown to be an additional criterion of safe fibrinolytic, antithrombin and long anticoagulant therapy. The presence of fibronectin fragments of 90-95 kDa at the 8th day of AMI is an independent additional prognostic factor of the trombic complications development at early hospital period. The Matrix metalloproteinases (MMP-2 and MMP-9) activity and specially their ratio is an additional prognostic criterion of the disease course and monitoring of the therapeutic methods efficiency. .5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close