Search academic texts

Information × Registration Number 0207U008820, 0107U011502 , R & D reports Title Complex research of a condition of the cores of a lifeproviding systems of an organism and definition of leading causes of infringement of their functioning at children who were born at irradiated parents. popup.stage_title Head Stepanova Eugenia I, Доктор медичних наук Registration Date 21-12-2007 Organization Research Centre for Radiation Medicine popup.description2 The work purpose: On the basis of complex clinical-laboratory and tool inspection to define leading mechanisms of infringements of functioning of the cores a life of providing systems of an organism of children who were born at irradiated parents. Object of researches: children who were born at parents, irradiated owing to accident on the atomic power station. Methods investigation: clinical, laboratory, statistical, mathematical. Carrying out of complex clinical -laboratory and tool inspection of children who were born from irradiated parents, has allowed to establish presence of features of functioning of bodies of breath, digestion, cardiovascular and immune systems. Their functional condition is influenced by a difficult complex of factors, leaders from which are the burdened heredity, an adverse micro-social environment, numerous medical and biologic risk factors at mother, presence of pathological conditions in the period born, chest and early children's age. Correlation communications between adose of an irradiation of a thyroid gland of mother, a dose of the general irradiation of parents and development immunodepressive conditions at children of the basic groups, and also increase of frequency of bronchial hyperreactance depending on activity 137Сs in a body of the child are revealed. One of the important mechanisms of development of variety of adverse effects in the first generation of descendants of the irradiated parents, is transgenerative transfer by a gene ache instability which in a combination to action endogens and exogens risk factors promotes a birth of children with the lowered adaptable possibilities, raises frequency of formation and realisation at them a somatic pathology. At children living in conditions of long receipt nuclear in an organism, operate as well other mechanisms among which the important role is played by activation fryradicals processes in an organism. Product Description popup.authors popup.nrat_date 2020-04-02 Close