Search academic texts

Information × Registration Number 0208U002234, 0105U002338 , R & D reports Title The study of neurobiological mechanisms and clinical-neuropsychological particularities of aggressive behavior, the role of emotional systems of brain in mechanisms of aggressive behavior popup.stage_title Head Vorobjova T. M.; Kut'ko I. I., Registration Date 23-01-2008 Organization Institute of neurology, psychiatry and narcology of Academia of medical sciences of Ukraine popup.description2 Object of study - laboratory rats, patients with mental disorders. Aim of study -creation of models of aggressive behavior and grounding of their neurobiological mecha-nisms, investigation of clinical neuropsychological peculiarities of . aggressive behavior in patients with acute mental disorders and psychoorganic personality disturbances. It is revealed that the cerebral mechanisms of adaptive aggressive behavior are rather complicated. They in-clude the three trigger mechanisms: ventromedial hypothalamus, septum, olfactorius, neocortex, which form "working ensembles" of functional structures in the emotional brain depending on sensitivity on some links in the chine of this complicated multileveled organization with doublings and supplements. They involve the activation block, that is: reticular formation of the middle brain, central gray substance, posterior hypothala-mus; the modulation block, that is: septum, complex amigdaloideus, hippocampus; the block of starting, con-trol and limitation, thatis neocortex. The leading mediatory system is cholinergic, the starting one is noradrenergic and dopaminergic, the starting and stresslimiting ones are serotoninergic. Such doublings are reasonable and are the factors of effective providing of aggressive behavior. The general mechanism of ag-gression formation in animals and humans is determined by the state of emotional fund. The factors of ag-gressive behavior initiation are as follows: deprivation of natural biological and social motivations, depriva-tion of acquired motivations, social isolation and alterations in hormonal and immunological status as well. Product Description popup.authors popup.nrat_date 2020-04-02 Close