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Information × Registration Number 0208U002566, 0102U003706 , R & D reports Title Study of the polymers of the microorganisms and viruses with purpose of creation of new medical products, diagnosticums,ferments and immunomodulators for needs of medicine and agriculture popup.stage_title Head Podgorsky Valentin Stepanovich, Registration Date 01-02-2008 Organization Zabolotny Institute of Microbiology and Virology Ukrainian NAS popup.description2 It was been created a microbial preparation for alcoholic and narcotic treatment. It was been described a new specious of Gram-negative halophilous bacteria Oceanimonas smirnovii. It was shown that almost 9% of Streptomycetes strains contain plasmid DNA of different shape;some of them possess unique restriction sites for a number of endonuclease. It has been determined that lypopolysaccharides of all investigated strains of Pseudomonas syringae are characterised by antimutagenous activity. It has been shown that granulated bacterial preparations on the basis of A.vinelandii IMV B-7076 and B.subtilis IMV B-7023 increase considerably sugar beet yield,tomatoes,cucumbers and wheat. It was shown the possibility of inactivization of regulated mycotoxine T-2 by the yeast D.polymorphus 396 strain;T-2 toxine is methabolized up to the number of less toxic compounds. It have been isolated from the soil two native strains-producers of avermectin Streptomyces avermitilis,capable to synthesize in conditions of the surface grow up to 36ml of substance in 1ml ethanol extract. Among derivatives of 6-azacitidin high antiadenoviral activity has been shown for 2'-3'-seko-5-methyl-6-azacitidin,but the transport analogue of 6-azacitidin N1 O-tetraacil-6-azacitidin was active as for Epstein-Barr virus. It has been revealed the means between viruses of vesicular stomatitis (VSV),hydrophobia and virus of curly potato dwarf (CPDV). It has been created the immune-fermentative test-system for diagnostics of Epstein-Barr virus (IFA-ATVEB-strip). It has been determined the wide spread of defect lysogeny in E.carotovora:from 104 investigated strains of this pathogene 88% possess determinants for macromolecular carotovoricins. It has been established models deletion sequences,insertions, repetitions,recombinations and other structural elements for elaborations of computer programs of its exposition.It have been elaborated algorythms of graphic visualization clasters of short identical elements in the greatest quantity of investigated sequences. It has been elaborated the condition of the depth cultivation of melanin Cladosporium cladosporioides 396,recommended for making of melanin-containing biomass in semi-production conditions.It has elaborated the method of obtaining of melanin pigment out of fungi biomass. It have been elaborated medical preparations of immunemodulating directed action on the basis of lectins of strains Bacillus subtilis 668 IMV,B.polymixa 102 KGU. It was shown that preparations of molecular complexes tiloron-yeast RNA is prospective for production of interferon of the 1 type preparations. It has been shown that glycocalycs of mollicutes consists of galactosamine,glucosamine,galactose,glucose;at that time when in glycocalycs of the studied strains of lactic acid bacteria these sugars haven't been detected Product Description popup.authors popup.nrat_date 2020-04-02 Close