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Information × Registration Number 0208U002712, 0105U000360 , R & D reports Title The role of spatial organization of calcium channels and stores in the signal transformation in neurons popup.stage_title Head Korogod Sergiy Mikhailovich, Registration Date 13-02-2008 Organization Dniepropetrovsk national university popup.description2 In mathematical models of electrical and diffusion processes in neurons at cellular and sub-cellular levels it is established that: the ratio of free cytosole and surface of ion exchange between cytoplasm and stores determines amplification or attenuation of calcium signals; metrical asymmetry of the dendritic arborization and kinetics of calcium exchange determine phase relationships between calcium and potential oscillations in different dendrites and formation of output signal in a neuron; the intracleft electrical field changes the driving potential of calcium current of presynaptic terminal and thus calcium concentration and calcium-dependent transmitter release with corresponding consequence for modulation of synaptic effectiveness Product Description popup.authors popup.nrat_date 2020-04-02 Close