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Information × Registration Number 0208U004112, 0107U007198 , R & D reports Title Study of molecular mechanisms of nicotinic acetylcholine receptor functionning in b-lymphocyte-derived cell lines / study of means for chemical modification of hyaluronic acid fragments aimed in optimization of cell adhesion popup.stage_title Head Skok M.V., Registration Date 14-02-2008 Organization A.V.Palladin Institute of Biochemistry of National Academy of Sciences popup.description2 It is shown that nicotinic acetylcholine receptors support proliferation and survival of DT40 cell line due to the intracellular entry of Ca ions and activation of signaling pathways controlled by Ca-calmodulin-dependent kinase, MAP kinase MEK ? and proteinkinase C. Short fragments of hyaluronic acid are obtained, and optimal methods of their conjugation to proteins that preserve the pro-angiogenic activity of these fragments are determined. Product Description popup.authors popup.nrat_date 2020-04-02 Close