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Information × Registration Number 0208U005376, 0107U010818 , R & D reports Title Functional characterization jff potential oncogenes HC gp-39, YKL-39, IGF-II-assocyated protein and regulatory mechanisms jf ion homeostasis in tumor cells popup.stage_title Head Bozhkov A.I., Registration Date 22-04-2008 Organization Kharkov national university named after V.N. Karazin popup.description2 Aim this project is the characteristic of the potential endogens expression in tumors of the encephalon on the RNA and protein level, and changes ionic homeostasis in tumor cells of carcinomas. Methods: RNA electrophoresis in denaturing agarose gels, RNA hybridization analysis. (Northern-hybridization), Determination of Nа+, K+- и Mg2+- АТРases activity, fluorescence of tryptophan remains of the membranes proteins. It has been shown production of the specific transcript of gene IGF-II in tumors of encephalon-meningioma. Specific transcript of the gene were revealed by method "numerical" Northern for ependymoma. It has been shown that in last stages of development of the astrocytic glioma potential oncogenes YKL-39 и IGF-II- are expressed. The microviscosity of the membrane lipids don't change. Product Description popup.authors popup.nrat_date 2020-04-02 Close